Brucellosis

New research from the Francis Crick Institute has found how the malaria parasite protects itself from toxic compounds in red blood cells. Malaria causes around 400,000 deaths globally each year. It is caused by Plasmodium parasites which are transmitted by mosquitoes and grow in a person's blood stream. In their study, published in Proceedings of the National Academy of Sciences USA , Crick researchers together with colleagues from Germany and Switzerland identified a protein used by the malaria parasite to protect itself from a toxic compound in red blood cells. They hope this could lead to the development of drugs that block this process. When the malaria parasite enters a red blood cell it digests haemoglobin, leading to the release of a compound called haem, which is toxic to the parasite if it is left loose inside the cell. The researchers found that to overcome this, the parasite uses a protein, called PV5, to control a process where free haem molecules are joined toget...

Editor’s note: This story was updated to correct the first name of Williamsport police Agent Jason Bolt. WILLIAMSPORT – A Williamsport man has admitted sexually assaulting a 6-year-old girl who later tested positive for gonorrhea. That testimony from Williamsport police Agent Jason Bolt on Tuesday was sufficient for District Judge Christian D. Frey to hold Daniel Prieto, 38, for court. Prieto is charged with rape of a child, statutory sexual assault, aggravated indecent assault of a child, involuntary deviate sexual intercourse with a child and corruption of minors. Bolt testified in a preliminary hearing conducted by Zoom that Prieto initially denied having sexual contact with the girl but confessed in a May 21 recorded interview. Police initiated their investigation on Feb. 8 when they responded to a report of a missing juvenile who was found 90 minutes later. The mother, while accompanying her daughter for an interview, revealed she discovered in early February she had contac...

In the rural town of San Vicente, in Sucre state, on Venezuela’s northern coast, Santana Marquez goes to the local clinic. Two days prior, he began to have fever, headache, shivering and tiredness in his body. He has experienced these symptoms before, having had malaria four times. He is convinced that he has contracted the disease again. Santana is 61 years-old; he has spent his entire life in the agricultural community of San Vicente and is dedicated to the cultivation of taro, bananas and cocoa. He lives in a humble house and his main concern is how to bring the daily bread to the table to feed his family. He has to walk to the local medical centre, where he is examined and tested with a rapid malaria test. With a simple prick to the earlobe and after waiting for a few minutes, it is possible to have the results almost immediately. Three pillars of malaria care and prevention Sucre is one of the states in Venezuela with the highest incidence of malaria. Its climate and vegetati...

By NewsDesk  @infectiousdiseasenews Yemeni medical officials reported 250,000 malaria cases during the past six months, according to a Mareb Press report (computer translated). Image/syafrani_jambe via pixabay This is the latest infectious disease outbreak facing the war torn country with a crumbling health infrastructure. Sources emphasized that “tropical epidemic diseases”, especially malaria, still constitute a real threat to the lives of Yemenis, especially with the continuation of the rainy season accompanied by the spread of mosquitoes that transmit the disease. Ibb, Amran, Dhamar, Sanaa and separate areas of Hodeidah are the areas being ravaged by malaria. Al Hudaydah governorate is leading in the number of cases with 55,000 cases and 3500 deaths. Medical sources in Sanaa say the actual numbers of malaria are higher than the reported numbers. In Ibb governate, more than 38,000 malaria cases have been reported. A medical source said that malaria has invaded more...

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The prejudice that has affected some communities during the Covid-19 pandemic is akin to that faced by gay men at the height of the Aids crisis, according to the creators of a play about Diana, Princess of Wales’s visit to the UK’s first Aids ward. The playwright Bren Gosling and producer Paul Coleman were young, gay men living in London in the 1980s and their play, Moment of Grace, goes back to that era, following the lives of three fictional characters who are affected by the royal’s opening of the Broderip ward at Middlesex hospital in April 1987. Coleman said there were parallels between how people with the two illnesses have been treated, with phrases such as “super-spreaders” echoing the “patient zero” tag that was wrongly attributed to a flight attendant thought to be responsible for introducing the disease to the US. “I think the way we reacted when Covid-19 came along does bear a lot of similarities,” said Coleman. “There’s the way people said ‘it comes from China’ – that w...

As Pride month comes to a close, we reflect on 40 years ago when the world lived through another epidemic that suffered from misinformation and government inaction — the AIDS crisis. In this episode, CNN Chief Medical Correspondent Dr. Sanjay Gupta speaks with CNN National Political Writer Brandon Tensley about lessons from the AIDS epidemic that could help the country better manage Covid-19 today. You can listen on your favorite podcast app or read the transcript below. Dr. Anthony Fauci, director, National Institute of Allergy and Infectious Diseases, 1984: This is a new disease, at least in the United States. Where it came from, we’ll discuss in a short while. But in the United States, it’s new. Dr. Sanjay Gupta: You probably recognize that voice by now — Dr. Anthony Fauci. But that wasn’t him talking about the coronavirus — that was him almost 40 years ago, talking about the AIDS epidemic. In the United States alone, more than 700,000 people have died from AIDS since the e...

Researchers at the University of Georgia have demonstrated that disease surveillance data can be used to predict certain infectious disease outbreaks. The team detected early warning signals of a 1993 resurgence of malaria in Kenya in case reports from the roughly 10 years before the outbreak began. Their findings appear in the Royal Society journal Biology Letters. The study was based on a theoretical framework for a disease forecasting system being developed by Distinguished Research Professor John Drake and his colleagues at the UGA Center for the Ecology of Infectious Diseases. It relies on the theory of “critical slowing down,” which predicts that telltale statistical patterns appear when a system under stress is nearing a tipping point—a point at which it changes irrevocably from one state to another. Tipping points occur in all kinds of systems, from financial markets to Earth’s climate. In the case of infectious diseases, it is the point at which conditions become favorable ...

Three pillars of malaria care and prevention Sucre is one of the states in Venezuela with the highest incidence of malaria. Its climate and vegetation make the area perfect for the proliferation of the Anopheles mosquito, which transmits the disease. Médecins Sans Frontières (MSF) performed more than 20,000 diagnostic tests in Sucre, just in 2019, of which more than 12,000 turned out to be positive. MSF has been present in the area since the last year, working with the Malaria Programme of the Regional Environmental Health Directorate on a strategy to reduce and control the disease. In seven healthcare centres across five municipalities in the state, MSF is working on three main pillars: early diagnosis and treatment; strengthening epidemiological surveillance and vector control activities; and health promotion. With this multi-tiered approach, the clinics in San Vicente, Agua Clarita, Guaca, Putucual, Caño Ajíes and Coicual, and the Yaguaraparo hospital are all supported by MSF, he...

A news station in Columbia, South Carolina recently received an influx of comments about various ailments people have endured after wearing a face mask out in public. One in particular stands out. A woman named Cheryl Gilbert shared how her husband went out on a business trip, and returned with a brand new case of CHLAMYDIA after wearing his face mask!  Yes, her husband told her he caught chlamydia because he was forced to wear a face mask. Y'all.. this just happened on our local news site.. what is life pic.twitter.com/wEvLEVzS9r — Just Jen (@Jenwifonen) June 25, 2020 Of course, people were quick to point out that it probably wasn't the facemask that gave her husband the STI.  Unfortunately, it is unknown of the message was clear for Gilbert as she deleted her Facebook shortly after the exchange. Via Metro

The report contains a thorough summary of Chlamydia Infection Test Market that includes several well-known organizations, key market players who are leading in terms of sales, variable market change, revenue, end-user demands, conformity through trustworthy services, restricted elements, products and other processes. Technical advancements, surplus capacity in developing markets, market bifurcation, globalization, regulations and environmental guidelines, production and packaging are some trends that are explained in the market report. The Global Chlamydia Infection Test Market will arrive at critical CAGR during estimate period 2020-2027. Furthermore, this report presents showcase rivalry circumstance among the sellers and friends profile, in addition, advertise value examination and worth chain highlights are shrouded in this report. Following Top Key Players are profiled with global positioning: Abbott ADI/American Diagnostica Agilent Technologies Chrono-Log Corgenix Decod...

It comes as the nation recognizes the 25th anniversary of National HIV Testing Day June 27, 2020 6:47 PM Marsalis McGhee Posted: June 27, 2020 6:47 PM Updated: June 27, 2020 9:17 PM LA CROSSE, Wis (WKBT) – Wisconsin Senator Tammy Baldwin is calling for federal funding for HIV/AIDS in the next coronavirus pandemic response package. It comes as the nation recognizes the 25th anniversary of National HIV Testing Day. Baldwin’s plan asks for more than 700 million dollars to go to programs for treatment, prevention, and housing for those affected with the disease. Specifically:   $500 million for HRSA’s Ryan White HIV/AIDS Program : Funding to support Ryan White Program providers and community-based organizations who are on the frontlines of the COVID-19 pandemic. Services and resources provided by this program include telehealth services, case management services, medications (prescription and over-the-counter), behavioral health services, and access to basic necessities, s...

Yellowstone bison bulls grazing in the early hours of the morning before being transported to the Fort Peck Indian Reservation/Don Woerner The bison pipeline from Yellowstone National Park to the Fort Peck Assiniboine and Sioux leaders in Montana continues to operate, with 11 more bison shipped from the park to the Fort Peck Indian Reservation. With that shipment Wednesday, 104 bison will have been successfully transferred to the reservation. This is the fourth relocation since April 2019 under a new program that diverts brucellosis-free Yellowstone bison from slaughter to tribal-led restoration efforts. Half or more of Yellowstone’s bison carry brucellosis, a cattle-introduced disease that, frankly, scares the hell out of ranchers. Brucella abortus , a bacterium thought to have reached the country from European livestock, can cause spontaneous abortions or stillbirths in bison and cattle. Until 2010, if two or more herds in a state contracted the disease, or if a single herd...

By Lauren E. Holz , Yu Cheng Chua , Maria N. de Menezes , Regan J. Anderson , Sarah L. Draper , Benjamin J. Compton , Susanna T. S. Chan , Juby Mathew , Jasmine Li , Lukasz Kedzierski , Zhongfang Wang , Lynette Beattie , Matthias H. Enders , Sonia Ghilas , Rose May , Thiago M. Steiner , Joshua Lange , Daniel Fernandez-Ruiz , Ana Maria Valencia-Hernandez , Taryn L. Osmond , Kathryn J. Farrand , Rebecca Seneviratna , Catarina F. Almeida , Kirsteen M. Tullett , Patrick Bertolino , David G. Bowen , Anton Cozijnsen , Vanessa Mollard , Geoffrey I. McFadden , Irina Caminschi , Mireille H. Lahoud , Katherine Kedzierska , Stephen J. Turner , Dale I. Godfrey , Ian F. Hermans , Gavin F. Painter , William R. Heath Science Immunology 26 Jun 2020

BCG is a weakened live bacteria (Mycobacterium bovis). It prompts the immune system to prepare to fight off future infection. Credit: www.shutterstock.com Researchers are investigating whether the anti-turberculosis vaccine bacillus Calmette-Guérin (BCG), which appears to protect recipients from other respiratory infections, could protect against COVID-19. Recent research suggests COVID-19's impact is more severe—with more illness and more deaths—in countries that do not routinely administer the BCG vaccine, which has been used since 1921 to prevent tuberculosis infection. The Serum Institute in India started large-scale clinical trials in April, testing 6,000 "high-risk" individuals, including health-care workers and close contact infected patients. Researchers in Australia and Europe are also investigating whether BCG protects individuals at high-risk of serious COVID-19 infection, such as the elderly and health-care workers. Indonesia is one of 17 countries...

During AIDS 2020 , HIV.gov will host three free opportunities to learn directly from key HHS leaders about current and planned activities to further Ending the HIV Epidemic: A Plan for America (EHE) . At each of the 20-minute sessions, participants will hear short remarks from either CDC’s Dr. Jono Mermin; HRSA’s Dr. Laura Cheever; or Harold Phillips, of the Office of Infectious Disease and HIV/AIDS Policy and then be able to ask specific questions about EHE via chat.  Registration will open early next week. All are welcome and there is no cost for participation. Subscribe to the HIV.gov blog and follow @HIVgov to hear us announce that registration is open and for information on other federal events at AIDS 2020 including live conference updates. Live with Leadership conversations will take place at the following times: Tuesday, July 7th at 2:00 pm ET – Dr. Jono Mermin, CDC Wednesday, July 8th at 11:00 am ET – Dr. Laura Cheever, HRSA Thursday, July 9th at 2:00 pm ET – Harol...

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San Francisco, CA, June 25, 2020 – With in-person health services limited due to COVID-19, Greater Than AIDS, a public information initiative of KFF, and Walgreens today announced a new program to provide 10,000 OraQuick® In-Home HIV Test kits to support expanded testing options in high-need areas. Local health agencies and community-based organizations will distribute the FDA-approved, self-administered tests at no cost to those unable to get tested in person. Just ahead of the 25th anniversary of National HIV Testing Day (June 27), the announcement comes at a critical time with the Centers for Disease Control and Prevention (CDC) estimating that HIV testing is down 50 to 70 percent since February. “As COVID-19 continues, we are seeing how it threatens other health responses,” said Tina Hoff, a senior vice president at KFF, which directs Greater Than AIDS. “This program aims to support frontline HIV service organizations as they transition to new ways of providing care during ...

The number of human tuberculosis (TB) cases that are due to transmission from animals, as opposed to human-to-human transmission, may be much higher than previously estimated, according to an international team of researchers. The results could have implications for epidemiological studies and public health interventions. "Tuberculosis kills 1.4 million people every year, making it the most deadly disease arising from a single infectious agent," said Vivek Kapur, professor of microbiology and infectious diseases and Huck Distinguished Chair in Global Health, Penn State. "India has the largest burden of human tuberculosis globally, with more than 2.6 million cases and 400,000 deaths reported in 2019. Additionally, the cattle population in India exceeds 300 million, and nearly 22 million of these were estimated to be infected with TB in 2017.  Kapur noted that the World Health Organization, World Organisation for Animal Health and Food and Agriculture Organization of th...

As the number of novel coronavirus cases continues to rise at an alarming rate across the globe, India has already reported close to 5 lakh cases and 15,000 deaths. The sad part is, even with dedicated guidelines, safety precautions and stringent lockdown measures, there is a huge spike in the number of recorded cases in India as the country reported 16,922 new cases in the last 24 hours. While the medical researchers and experts are working round the clock to develop a cure to combat the highly infectious contagion, there is still no definite date for rolling out a vaccine fit for human use. The lurking danger apart from the COVID pandemic In addition to the deeply worrying statistics of the novel coronavirus pandemic, there is yet another grave danger lurking in the country. According to the annual report of the national tuberculosis elimination programme, India reported over 24.04 lakh tuberculosis cases in the year 2019 and notified more than 79 thousand death due to the severe ...

More Yellowstone bison went to the Fort Peck Indian Reservation this week, pushing the total number of bison that have been quarantined and released there in the past year above 100. On Wednesday, 11 bison were shipped from corrals near Corwin Springs to the reservation, according to a news release from Defenders of Wildlife and the Fort Peck Tribes. It was the fourth shipment since April 2019, bringing the total number of bison brought there for the final stage of brucellosis quarantine to 104. And more are likely coming. About 150 bison are at different parts of the quarantine process at corrals either in Yellowstone National Park or just outside it, according to Chris Geremia, a Yellowstone bison biologist. Some of the bison could be ready to move to Fort Peck as soon as this winter. Advertisement The numbers keep stacking up, and though the process takes a long time, Geremia said it’s the right thing to do. “We’ve been trying for a long time to get live bison...