Brucellosis

Introduction The skin is the largest organ of the body and home to a vast array of microbes. 1 Phyla that dominate the skin are Actinobacteria, Proteobacteria, Bacteroidetes, and Firmicutes, with more than 60% of the bacterial species belonging to three genera, including Staphylococcus (Firmicutes); Corynebacterium (Actinobacteria), and Propionibacterium (Actinobacteria). 2 Sites rich in sebaceous secretion are preferentially colonized by lipophilic bacteria such as Cutibacterium acnes (previously known as Propionibacterium acnes ), whereas moist locations such as skin folds are favored by Corynebacterium spp. and Staphylococcus aureus. S. epidermidis is one of the most abundant bacterial species of the skin microbiome. It is a mutualistic, Gram-positive, facultative anaerobe that constitutes up to 90% of the aerobic resident flora, and certain strains have been associated with skin health. 3 Multiple skin conditions have been associated with alterations in the diversity ...

AJMC® : Hello, I'm Matthew Gavidia. Today on the MJH Life Sciences' Medical World News, The American Journal of Managed Care ® is pleased to welcome Dr Nicki Niemann, neurologist at the Muhammad Ali Parkinson Center and an assistant professor of neurology at Barrow Neurological Institute. Dr Niemann additionally served as a co-author of a review article titled "Parkinson's Disease and Skin." Great to have you on, Nicki. Can you just introduce yourself and tell us a little bit about your work? Dr Niemann : So, I'm a neurologist by training. I did my training at Baylor College of Medicine in Houston, Texas, and then I did my mood disorders fellowship with the same institution under the mentorship of Dr Joseph Jankovic, who's one of the co-authors on the review article that we're talking about today. I'm originally from Denmark, where I was born and raised and where I went to medical school at the University of Copenhagen before relocating to f...

INTRODUCTION The skin epithelial immune microenvironment deploys several mechanisms to regulate internal and environment-derived stress signals. While tolerance is induced toward innocuous factors, invasion of pathogens and contact with damaging substances activate keratinocytes and skin-resident immune cells to initiate proinflammatory processes resulting in skin-associated inflammation. Mechanisms for resolution and tissue recovery are necessary to maintain a balanced homeostasis and prevent the development of cutaneous immunopathologies ( 1 ). The immunosuppressive effect of glucocorticoids (GC) is widely accepted and exploited in the therapy of inflammatory diseases ( 2 ). Despite their pleiotropic and adverse side effects, GC represent the mainstay in clinical therapy for more than 70 years, as diverse inflammatory disorders are still efficiently treated using synthetic GC ( 3 ). However, the potential impact of endogenous GC in the regulation of local inflammation in severa...

LINCOLN, Neb. (KOLN) - During a traffic stop this week, officers with the Lincoln Police Department discovered nearly 40 grams of meth and a number of pills in the driver's purse. Around 7 p.m. on Monday, an officer stopped a silver 2005 Buick Sedan with no license plates near 14th and B Streets. LPD said the driver, identified as 37-year-old Risa VanMeter, wasn't able to provide a drivers license or paperwork for the car. Polcie said VanMeter was acting very nervous and the officer questioned her about her behavior. LPD said she denied being in possession of anything illegal and allowed the officer to search the car. According to police, when officers opened the car door, there was a strong smell of marijuana coming from the car. Officers said they located a purse that contained 39.8 grams of methamphetamine which is equivalent to 200 individual user doses, four Morphine Sulfate pills, seven Alprazolam pills and 10 Dextroamphetamine pills. LPD said the pills are al...

Intertrigo is a skin condition that causes a rash in folds of the skin, such as under the breasts, in the groin, or under the tummy fold. It happens when areas of moist skin rub together. Bacteria and yeast can grow in this environment, leading to an infection. In this article, we describe what intertrigo is, what it looks like, and what causes it. We also cover diagnosis, treatment, and prevention. Intertrigo is a skin condition that happens when folds of skin chafe against each other. It usually develops in the inner thighs or armpits, or under the breasts or tummy fold. Some people may experience yeast or bacterial infections in the folds of skin. Areas of moist skin rubbing together cause intertrigo. The warm, damp environment makes the skin conducive to irritation and the growth of yeast and bacteria, which can lead to an infection. While it can happen at any age, intertrigo tends to affect infants, older people, and those with a reduced ability to ...