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Xeljanz (tofacitinib citrate) is a daily oral medication that is approved to treat moderate to severe cases of rheumatoid arthritis (RA), psoriatic arthritis, and ulcerative colitis in adults. Xeljanz is part of a group of medications known as JAK (Janus kinase) inhibitors, which decrease inflammation by helping block an overactive immune response.   Xeljanz is available in a 10 milligram (mg) twice daily dose, and a 5 mg twice daily dose, depending on your condition. It can be used alone or in combination with certain other medications, and is typically prescribed for patients who haven't had success with other classes of drugs. While Xeljanz can be an effective treatment for some people, there are both mild and serious side effects associated with the drug that you should discuss with your doctor before using. Grace Cary / Moment / Getty Images Common Side Effects Research suggests that RA patients using Xeljanz can experience a significant reducti...

Nabumetone is the generic version of a nonsteroidal anti-inflammatory drug (NSAID) of the now discontinued brand name Relafen. Used to treat mild to moderate pain, nabumetone works by reducing hormones in the body that cause inflammation and pain. It is particularly effective at relieving symptoms of arthritis(e.g., inflammation, swelling, and joint pain). Nabumetone is available in pill/tablet form, and only by prescription. Nabumetone has a "black box" warning from the U.S. Food & Drug Administration (FDA). Black box warnings alert patients and doctors to potentially dangerous side effects caused by a medication.  PORNCHAI SODA / iStock / Getty Images Uses Nabumetone is used to reduce pain, joint stiffness, and swelling caused by certain types of arthritis, most commonly osteoarthritis and rheumatoid arthritis.    Off-Label Uses Nabumetone is typically prescribed to individuals living with arthritis. It is generally not prescribed by d...

THURSDAY, Feb. 18, 2021 (HealthDay News) -- You finally managed to score an appointment to be vaccinated against the new coronavirus and you're a little nervous about side effects, so taking a painkiller right before you get your shot seems like a smart idea. Not so fast, says the U.S. Centers for Disease Control and Prevention. Instead, the agency is telling people not to take pain medications like Motrin, Advil or Tylenol before getting their COVID-19 vaccines. Why? It's possible that taking a painkiller before getting a vaccine will result in a "decrease in antibody response," explained Dr. Gregory Poland, director of the Vaccine Research Group at the Mayo Clinic in Rochester, Minn. Although the odds of a diminished immune response aren't really known, Poland said it's better to suffer the side effects than take the chance of making the vaccine less effective. "After receiving the vaccine, if one develops symptoms that they feel they want to tr...

ODESSA, Texas (KOSA) - Some people have reported symptoms of fever and fatigue after getting the second dose of the COVID-19 vaccine. But is the usual remedy of over-the-counter pain relievers safe to take? Around 40 percent of people who received a second dose of the vaccine are likely to get side effects like a fever or body aches. But you might want to think twice before popping an Advil or Tylenol to relieve the pain. Pain relievers like Advil or Tylenol are designed to block the chemical products that the body responds to areas of pain with. So does the medication affect the COVID-19 vaccine? There is not much data yet, but some studies suggest that taking a preventative painkiller before getting the COVID-19 vaccine could slow down your immune system's response. "Could it block the response? Theoretically, sure it could block the response a little bit. So we tell them don't take it before. Wait to see if you actually have side effects and if you do, the...

Some patients are preemptively taking over-the-counter pain medications before receiving a Covid-19 vaccine to stave off potential side effects, such as muscle aches or pains—but researchers warn that common painkillers may reduce the immune system's response to some vaccines. Webinar series: 'Stay Up to Date' with the latest vaccine news and more Could preemptive painkiller doses interfere with the Covid-19 vaccine? According to ABC News, the side effects of currently available Covid-19 vaccines, which are generally mild, are spurred by the way the vaccines activate the body's defense system to build immunity to the new coronavirus. In other words, these side effects are evidence the vaccine is doing exactly what it should be doing—and that's why some experts are cautious about preemptively taking painkillers, ABC News reports. Specifically, experts are concerned that taking painkillers may slow the immune system's response to the vaccine, reducing th...

Feb. 1, 2021 -- More people with fever and body aches are turning to common pain relief drugs to ease symptoms, but the drugs have come under new scrutiny as investigators work to determine whether they are a safe way to relieve the pain of COVID-19 vaccination or symptoms of the disease. Early on in the pandemic, French health officials warned that nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, could worsen coronavirus disease, and they recommended switching to acetaminophen instead. The National Health Service in the United Kingdom followed with a similar recommendation for acetaminophen. But the European Medicines Agency took a different approach, reporting "no scientific evidence" that NSAIDs could worsen COVID-19. The FDA also opted not to take a stance. The debate prompted discussion on social media, with various reactions from around the world. It also inspired Craig Wilen, MD, from Yale University School of Medicine in New Haven, CT, and his...

Naprosyn (naproxen) is a non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain and inflammatory diseases. It is also used to help relieve menstrual cramps and reduce fever.   The use of Naprosyn is approved by the U.S. Food and Drug Administration (FDA) for a number of conditions, including acute gout, bursitis, various forms of arthritis, tendonitis, and primary dysmenorrhea (painful periods).   Naprosyn can be found over the counter under the brand name Aleve, but it is also available as a prescription based on specific needs. Prior to taking a new medication, speak with your primary care physician to make sure it is safe and right for you. Jose Jonathan Heres / Getty Images Common Side Effects Many pain medications come with side effects, and Naprosyn is no different. Side effects from medications can vary in severity and likelihood, however, since people respond to medications differently. It can therefore be...

Arthrotec is a combination of diclofenac and misoprostol. The combination of these two medications helps make Arthrotec a good option for many people who have arthritis. Peter Dazeley/Getty Images Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and stiffness in the joints. Misoprostol is added to help protect the stomach from the potentially damaging effects caused by taking an NSAID such as diclofenac. This combination is a good option for those who have a history of stomach ulcers or gastrointestinal bleeding and need help controlling the discomfort arthritis creates.  Currently, Arthrotec is only available in tablet form. For this medication to be most effective, it is essential to take the tablet whole. Do not take a tablet that is cut, crushed, or broken in any way. Common Side Effects When you start this medication, you may experience some side effects that are unpleasant but not life-threatening. In many cases, these ...

Ringworm is characterized by scaly red patches, or "rings," on the skin. But many other skin conditions can cause the same symptom. This article looks at skin conditions that resemble ringworm and the range of treatments and strategies for prevention. Pityriasis rosea is a common, mild skin rash that usually lasts for 6–8 weeks. It causes a scaly pink patch, about 2–10 centimeters (cm) in diameter, to form on the skin. When the rash is smaller, it can be mistaken for ringworm, and it usually develops on the torso or neck. The rash is not painful but may be itchy. In dark-skinned people, it may appear grey, dark brown, or black. In light-skinned people, it may appear pink or red. A viral infection, such as herpes, is likely the cause of pityriasis rosea. But it is not contagious and cannot spread through physical contact. Learn more about pityriasis rosea here. Contact dermatitis is a type of eczema that forms in response to a substance irritati...

Ringworm is a common fungal infection, and it usually forms a circular or oval-shaped rash. The fungi responsible for ringworm thrive in hot, moist environments, such as the tropics, or more specifically, locker rooms and indoor pools. Sometimes, we classify ringworm by the area of the body that it affects — other names include jock itch and athlete's foot. A doctor may also refer to the rash as tinea or dermatophytosis. Anyone, of any age, can develop this infection. On darker skin, the rash may be brown or gray. On lighter skin, it may be red. The rash usually develops 4–14 days after the person comes into contact with the fungi and develops the infection. A person with a weakened immune system is more likely to experience symptoms of the infection. Beyond the rash, ringworm can occur with itchiness, cracked skin, and hair loss. Other symptoms depend on the location of the infection, which may be: The feet Commonly known as athlete's foot, ringworm...

The most common cause of a circular rash on the skin is ringworm, but other issues can also leave this distinctive mark. A doctor diagnoses the cause of a rash after examining it and asking about symptoms. They may recommend oral medication, a topical cream, or strategies for avoiding triggers. In this article, learn more about the issues that can cause this rash and how to treat them. Despite its name, ringworm is a fungal skin infection — it is not caused by a worm or any other parasite. The infection got its name because it causes a rash that is usually circular, with a thin raised ring around the edge that may look like a worm. Symptoms The circular rash may initially measure a few centimeters across, and it can grow without treatment. It may look like a round, flat patch, and the middle of the rash tends to heal first. On lighter skin, a ringworm rash is red or pink, and on darker skin, it is silver or brown. The skin around the rash may be dry or scaly, an...

Your skin is your body's largest organ, so it's not surprising that plenty can (and does) go wrong with it. Skin rashes are a common issue that can impact pretty much anyone, no matter your age, hygiene, or medical history. "A rash is essentially inflammation in the skin that can be caused by either an external exposure or an internal factor," says Joshua Zeichner, M.D., director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York City. Basically, a rash is your skin's way of telling you something is up, whether you've been exposed to an irritant or you have an underlying medical condition. The unifying feature of all rashes is inflammation, Dr. Zeichner explains. That inflammation could be minor or could greatly impact the color, texture, or feeling of your skin—it all depends on the type and severity of your rash. (Note: Some of the chronic skin conditions listed below, like acne and rosacea, might not be considered ras...