Antibiotics in the clinical pipeline in October 2019 - The Journal of Antibiotics



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Side Effects Of Arikayce: What You Need To Know

ALLERGIC REACTION

For some people, Arikayce can cause an allergic reaction. Symptoms of allergic reaction can be mild to serious.

Mild allergic reaction symptoms may include:

Symptoms of a serious allergic reaction may include:

Inflammation in the lungs from an allergic reaction to Arikayce was a rare side effect that happened in the drug's studies.

Symptoms of lung inflammation may include:

What might help

If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest a treatment to manage your symptoms and can determine whether you should continue Arikayce treatment.

If you have symptoms of a severe allergic reaction, such as swelling or difficulty breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

If your doctor confirms you've had a serious allergic reaction to Arikayce, they may have you switch to a different treatment.


Insmed's Strategic Growth And Market Potential Drive Buy Recommendation

Leerink Partners analyst Joseph Schwartz has reiterated their bullish stance on INSM stock, giving a Buy rating on November 8.

Joseph Schwartz's rating is based on Insmed's strategic management decisions and promising market potential. The company recently closed their $500 million ATM equity offering, which indicates a strong focus on maximizing shareholder value. Management believes that the remaining ATM capacity was relatively insignificant compared to the company's size and growth opportunities, suggesting a prudent financial strategy.Furthermore, Insmed's promising ASPEN data positions them to potentially access the lucrative non-cystic fibrosis bronchiectasis market, valued at over $5 billion at peak. Schwartz acknowledges the company's consistent execution in clinical, regulatory, and commercial areas, which contributes to a positive outlook. While the closure of the ATM has fueled acquisition speculations, the company's strategic alignment with investor interests and robust cash position supports the Buy rating.

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Insmed (INSM) Company Description:

Insmed, Inc. Is a biopharmaceutical company on a mission to transform the lives of patients with serious and rare diseases. Its first commercial product is ARIKAYCE (amikacin liposome inhalation suspension), which is approved in the United States for the treatment of Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. The MAC lung disease is a rare and often chronic infection that can cause irreversible lung damage and can be fatal. Its earlier-stage clinical pipeline includes INS1007, a novel oral reversible inhibitor of dipeptidyl peptidase 1 with therapeutic potential in non-cystic fibrosis bronchiectasis and other inflammatory diseases, and INS1009, an inhaled formulation of a treprostinil prodrug that may offer a differentiated product profile for rare pulmonary disorders, including pulmonary arterial hypertension. The company was founded in 1988 and is headquartered in Bridgewater, NJ.


Insmed's Options: A Look At What The Big Money Is Thinking

Financial giants have made a conspicuous bearish move on Insmed. Our analysis of options history for Insmed INSM revealed 13 unusual trades.

Delving into the details, we found 7% of traders were bullish, while 76% showed bearish tendencies. Out of all the trades we spotted, 10 were puts, with a value of $855,036, and 3 were calls, valued at $419,310.

Expected Price Movements

Based on the trading activity, it appears that the significant investors are aiming for a price territory stretching from $62.5 to $85.0 for Insmed over the recent three months.

Analyzing Volume & Open Interest

In today's trading context, the average open interest for options of Insmed stands at 2968.25, with a total volume reaching 15,604.00. The accompanying chart delineates the progression of both call and put option volume and open interest for high-value trades in Insmed, situated within the strike price corridor from $62.5 to $85.0, throughout the last 30 days.

Insmed Option Volume And Open Interest Over Last 30 Days

Biggest Options Spotted: Symbol PUT/CALL Trade Type Sentiment Exp. Date Ask Bid Price Strike Price Total Trade Price Open Interest Volume INSM CALL TRADE BULLISH 01/17/25 $1.2 $0.75 $1.2 $85.00 $360.0K 7.1K 3.0K INSM PUT SWEEP BEARISH 01/17/25 $4.1 $3.8 $4.06 $62.50 $150.3K 504 2.3K INSM PUT SWEEP BEARISH 01/17/25 $4.5 $3.4 $3.9 $62.50 $142.3K 504 365 INSM PUT SWEEP BEARISH 01/17/25 $4.0 $3.7 $4.0 $62.50 $138.4K 504 1.5K INSM PUT SWEEP BEARISH 01/17/25 $4.0 $3.7 $4.0 $62.50 $123.2K 504 746 About Insmed

Insmed Inc is a global biopharmaceutical company transforming the lives of patients with serious and rare diseases. The company's first commercial product is ARIKAYCE (amikacin liposome inhalation suspension), approved in the US for the treatment of Mycobacterium Avium Complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. The company's earlier-stage clinical pipeline includes Brensocatib, a novel oral reversible inhibitor of dipeptidyl peptidase 1 with therapeutic potential in non-cystic fibrosis bronchiectasis and other inflammatory diseases; and INS1009, an inhaled formulation of a treprostinil prodrug that may offer a differentiated product profile for pulmonary arterial hypertension.

After a thorough review of the options trading surrounding Insmed, we move to examine the company in more detail. This includes an assessment of its current market status and performance.

Where Is Insmed Standing Right Now?
  • With a trading volume of 891,951, the price of INSM is down by -0.03%, reaching $66.27.
  • Current RSI values indicate that the stock is may be approaching oversold.
  • Next earnings report is scheduled for 94 days from now.
  • Professional Analyst Ratings for Insmed

    2 market experts have recently issued ratings for this stock, with a consensus target price of $97.5.

    Unusual Options Activity Detected: Smart Money on the Move

    Benzinga Edge's Unusual Options board spots potential market movers before they happen. See what positions big money is taking on your favorite stocks. Click here for access. * In a cautious move, an analyst from Truist Securities downgraded its rating to Buy, setting a price target of $105. * Reflecting concerns, an analyst from HC Wainwright & Co. Lowers its rating to Buy with a new price target of $90.

    Options trading presents higher risks and potential rewards. Astute traders manage these risks by continually educating themselves, adapting their strategies, monitoring multiple indicators, and keeping a close eye on market movements. Stay informed about the latest Insmed options trades with real-time alerts from Benzinga Pro.

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